You should make sure that you have given some thought to the following questions before you go out and buy a system so that you can be certain that it will fulfill your requirements. If you do this, you will be able to make an informed decision about whether or not to purchase the system.
The vast majority of products that have been designed specifically for freeze drying contain only water as a solvent. This is the case for almost all of these products. In addition to this, it does not react with any of the other substances that are present in the freeze dryer, which makes it a substance that is very simple to work with. This is because it does not react with any of the other substances that are present in the laboratory freeze dryer. It is possible to construct machines that are resistant to corrosion by replacing certain components, like the chamber door or the manifold, with stainless steel instead of acrylic. This is one method for accomplishing this goal. Because of this, the machine is better able to withstand environments that are corrosive. However, not every solvent can be used for freeze drying because some of them have a freezing temperature that is too low, and others have a nature that makes them corrosive, both of which make them inappropriate for use in this process. You absolutely need to get on the phone with your provider as soon as possible and start discussing this matter.
Freeze drying is a process that can be applied to products for a variety of different reasons, including the maintenance of a product's flavor or appearance, the extension of the shelf life of the product, the formation of a particular structure, the reduction in the rate of biological activity, and the avoidance of deterioration. Freeze drying can be applied to products for a variety of different reasons, including the extension of the shelf life of the product. When it comes to the regulatory requirements and cost tolerances, various products can have very different expectations of what is expected of them. For example, freeze-dried strawberries for a breakfast cereal will not be subject to the same level of regulatory burden as an injectable vaccine, but the price of these strawberries will be significantly more sensitive to changes. It is helpful to think about writing an User Requirement Specification (URS), which is a document that clarifies all of your requirements. If you want to avoid ambiguity and confusion, it is helpful to think about writing an URS.
Which type of unit or container are we going over at this particular moment in time?
When products are freeze dried, a wide variety of containers are used, such as flasks for research and development products, vials for pharmaceuticals, bulk trays for slurry, and 96 well plates for diagnostics. It is possible that certain things, such as waterlogged paper or timber, do not require any containers at all. This is because the size of the items in question determines whether or not this is the case. Vials, 96-well plates, and trays are the containers that work best in freeze dryers with shelves, whereas flasks work best in manifold dryers. Flasks are better suited for manifold dryers.
When you are filling the containers with the product you are selling, you need to exercise an increased level of caution if the product is a liquid or a slurry because it has the potential to spill out of the container. The length of time it takes for the product to dry after Drawell has been manufactured is directly proportional to the increase in the product's depth. Before being sealed and placed in the freezer, for instance, freeze drying flasks should only be filled one quarter or one third of the way full before being frozen. This recommendation is contingent on the kind of freezing method that you use.
In order to successfully attach a container to a manifold at a later time, it is necessary to prefreeze the container first. The task of freezing flasks full of product in a manner that would result in the greatest amount of drying being accomplished led to the development of freezers known as shell baths. These freezers were designed specifically for this purpose.
In order to prepare the product for use, how much of it would you like to dehydrate in the freezer first?
It is imperative that the total capacity of the condenser be higher than the volume of the batch that is being processed; for example, a condenser with a total capacity of 5 liters should not be used to process a batch that is equal to 5 liters in volume. This is because the total capacity of the condenser must be higher than the volume of the batch in order for it to function properly. This is due to the fact that in order for the condenser to function correctly, the total capacity of the device must be greater than the volume of the batch being processed. To be more specific, this is done in order to make accommodations for the unpredictable flow rates of the vapour. It is especially important to keep this in mind when working with large volumes or extremely wet products, as well as manifolds that have a significant number of flask attachments.
It is possible that the dimensions of the container itself place a limit on the amount of product that can be stored in the chamber of freeze dryers that are equipped with shelves. This is because the shelves in the chamber take up some of the available space.
We require specific information regarding the location of the freeze dryer within the given space.
Both temperature-controllable shelf systems and manifold systems can be purchased in either a floor-standing or bench-top configuration. Both options are suitable for use in laboratories. Floor-standing systems are the only ones that come with the option of larger condenser capacities as well as drying chambers. Floor-standing systems also come with the option of being purchased separately. Systems that are floor-standing have the additional option of being freestanding as well. Temperatures should be kept in the range of 20 to 22 degrees Celsius, and relative humidity levels should be kept at or below 70 percent at all times. The systems will continue to operate even if the temperature is outside of this range; however, the cooling process may be slowed down, and it is also possible that they will not reach temperatures that are particularly low.
It is possible to construct many different kinds of systems in many different configurations, which makes it possible for them to be adapted to fit in a variety of spaces or to be suitable for use in cleanrooms; however, it is imperative that you discuss these requirements prior to beginning construction!
